Journey of Tuberculosis Control in India: From then till now

From there to here, from now till then: buying and borrowing public management reforms

Most reformers don't invent completely new ideas they buy or borrow management ideas and techniques from elsewhere. They bring things from 'there' to 'here'. Merchants in this trade include governments, management consultants, international organizations and even some academics. Money changes hands, but that is not the only currency. Influence, prestige and status are also involved in these tra...

Schizophrenia: Then and Now

EPS—Then and Now

"Slime" played a brief and spectacular role in the 19th century founded by the theory of primordial slime by Ernst Haeckel. However, that substance was never found and eventually abandoned. Further scientific attention slowly began in the 1930s referring to slime as a microbial product and then was inspired by "How bacteria stick" by Costerton et al. in 1978, and the matrix material was conside...

Then and Now

Fluoroquinolones: then and now.

Fluoroquinolones were discovered in the 1960s as a derivative of the antimalarial drug chloroquine. Over the past 40 years, many fluoroquinolones have been developed for use in human and veterinary medicine. As with all classes of antibiotics, resistance to fluoroquinolones is a serious concern, and multiple avenues for resistance are being investigated. Resistance-associated point mutations in...